13th Zinc Biology Asia/Oceania Regional Zoom Meeting

Category : Events | Zinc - Asia/Oceania Posted on 2023-01-11 20:05:23
13th Zinc Biology Asia/Oceania Regional Zoom Meeting

Speaker: Professor Motohiro Nishida.
Title: "Zinc as a cardiotonic mediator". 

Impaired baroreflex-dependent cardiac contraction (positive inotropy) through sympathetic nerve activation is a major cause for bad prognosis of heart failure. We found that a local Zn2+ influx through transient receptor potential canonical (TRPC) 6 channel potentiates (3 -adrenoceptor ((3AR) -stimulated cardiac positive inotropy in mice. TRPC6-mediated Zn2+ influx boosts a1 adrenergic receptor (AR)-stimulated (3AR/G5 -dependent signaling in rat cardiomyocytes by inhibiting (3 -arrestin-mediated (3AR internalization. I will introduce that TRPC6-mediated Zn2+ influx with a1AR stimulation enhances baroreflex-induced positive inotropy which may be a new therapeutic strategy for chronic heart failure.

Zoom meeting details are: 
Join Zoom Meeting

Meeting ID: 878 3737 1158
Password: 46632497
Contact: Leigh Ackland; Meeting organizer of ISZB-Asia/Oceania: leigh.ackland@deakin.edu.au

To be held on January 24, 2023. 
5 pm Australia/Melbourne time (this is 6pm AEDT Australian Daylight Saving Time. Zoom is using AEST so log in at 6pm, not 5pm)
4 pm Japan/Tokyo time
3 pm China/Beijing time
3 pm Taipei/Taiwan time
8 am London time
9 am European time
3 am US EDT
7 pm New Zealand time (this is 7 pm New Zealand Standard Time but 8 pm Daylight Saving Time. Zoom is using New Zealand Standard Time so log in at 8 pm, not 7 pm)